How to Open The Seraphites Safes in The Last of Us Part II

In The Last of Us Part II, the chapter “The Seraphites” presents players with the challenge of making their way through dangerous territory while trying to reach the hospital. Along the way, there are two safes that are crucial for collecting valuable supplies such as ammo and supplements. In this guide, we’ll walk you through the steps to find both safes, and we’ll provide the safe combinations to help you unlock them.

Apartment Safe – Safe #1

Location:
After navigating the streets in The Seraphites, you’ll come across a white truck on Route 5. Climb onto the truck to access the apartment building. Head through the door and enter the first apartment you encounter. Once inside, you’ll find a bedroom with a brown door. Behind this door is the safe.

Safe Combination:
The combination for this safe is 10-08-83. You can find the code by examining the calendar in the bedroom of the apartment, which provides the date. Additionally, the Evacuation Letter collectible in the same room offers context for this code.

Contents:
Opening the safe will reward you with a mix of valuable supplies, including ammunition and supplements, both of which will help you on your journey.

Pharmacy Safe – Safe #2

Location:
Just before you reach the hospital, you’ll need to go through Weston’s Pharmacy. Look around the pharmacy and find a hole in the wall between two shelves. Crawling through this hole will lead you into a back room, where the pharmacy safe is located.

Safe Combination:
The combination for the pharmacy safe is 38-55-23. You can find the code by reading the Pharmacy Note behind the pharmacy counter. The note offers a clue for unlocking the safe.

Contents:
Inside the pharmacy safe, you’ll find a variety of useful supplies, including ammunition, which can be crucial as you face tougher enemies in the later sections of the game.

Additional Tips

• The Seraphites chapter is filled with dangerous enemies and intense stealth sections. Take your time to explore each area thoroughly, as the safes and other collectibles are often hidden in less obvious places.
• If you’re having trouble spotting the safes, remember that they are often tucked away in rooms behind locked doors or through hidden passages. Be sure to check every corner and backtrack if needed.
• Always look for notes and other collectible items in each area. These not only help you unlock safes but also provide additional lore and context to the story.

The safes in “The Seraphites” chapter are an excellent way to gather important resources that will aid you in the challenges ahead. By following this guide, you’ll be able to access the apartment and pharmacy safes, ensuring you’re well-equipped for the journey to the hospital. Don’t forget to take your time to explore and enjoy the environment while grabbing these essential supplies.

For more help collecting everything in The Last of Us Part II, check out our comprehensive collectibles guides to find every item in the game.

We hope this guide helps you unlock the safes and find the supplies you need. If you have any questions or need further help, feel free to leave a comment below!