The Binding of Isaac Afterbirth Plus Bosses

The Binding of Isaac Afterbirth Plus has been out since January 3rd and there are a few new bosses to fight. These bosses range from simple designs to more complex ones, but all of them add a fresh set of challenges to face. Below is our list of The Binding of Isaac Afterbirth Plus bosses.

Rag Mega

The Binding of Isaac Afterbirth Plus Bosses

Rag Mega is the new Mega variant of the Rag Man boss.



Base HP: 110

Location: Chapter 2 – CAVES


Big Horn

The Binding of Isaac Afterbirth Plus Bosses

Big Horn is the new variant form of Little Horn.



Base HP: 480

Location: Chapter 2 – CAVES and CATACOMBS


Sisters Vis

The Binding of Isaac Afterbirth Plus Bosses

Sisters Vis are a new variant form of the Cage.

Base HP: 500

Location: Chapter 3 – DEPTHS and NECROPOLIS


Delirium

The Binding of Isaac Afterbirth Plus Bosses

via Binding of Isaac Gamepedia Wiki



Delirium is a new boss that takes on the shape of other bosses from throughout the game.

Base HP: 10000

Location: Chapter 4 – THE VOID (new area)


Ultra Greedier

The Binding of Isaac Afterbirth Plus Bosses

via Binding of Isaac Gamepedia Wiki



Ultra Greedier is the second phase of Greed in the Greedier Game mode. The boss takes on the appearance of the gold statue you see when completing Greed Mode.

Base HP: 2500

Location: Last Room in Greedier Mode




In total there are about 5 new bosses (really only 1 if you don’t count the mega/variant versions) in The Binding of Isaac Afterbirth Plus. Each boss is slightly harder than previous forms and should be approached with caution. Delirium and Ultra Greedier are especially difficult and represent the really hard content of Isaac. After a few tries, you will get the hang of the new patterns and be good to go!

Check out more Isaac Walkthroughs

Last two image sources here

What did you think of this list of The Binding of Isaac Afterbirth Plus Bosses? Want to add anything? Don’t want to add anything? Let me know in the Pit below.

enricofairme

Enricofairme is the founder and lead writer on holdtoreset.com. He has been creating content about video games for the past 6 years. You can follow Eli on Twitter @enricofairme.

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